{"id":408588,"date":"2024-10-20T05:31:26","date_gmt":"2024-10-20T05:31:26","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bsi-22-30397817-dc\/"},"modified":"2024-10-26T10:04:00","modified_gmt":"2024-10-26T10:04:00","slug":"bsi-22-30397817-dc","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bsi-22-30397817-dc\/","title":{"rendered":"BSI 22\/30397817 DC"},"content":{"rendered":"
PDF Pages<\/th>\n | PDF Title<\/th>\n<\/tr>\n | ||||||
---|---|---|---|---|---|---|---|
7<\/td>\n | Foreword <\/td>\n<\/tr>\n | ||||||
8<\/td>\n | Introduction <\/td>\n<\/tr>\n | ||||||
9<\/td>\n | 1 Scope 2 Normative references 3 Terms and definitions <\/td>\n<\/tr>\n | ||||||
14<\/td>\n | 4 General considerations 5 Risk management for microbiological contamination 5.1 Risk management in manufacturing process <\/td>\n<\/tr>\n | ||||||
16<\/td>\n | 5.2 Risk management in microbial testing 6 Selection of a fit-for-purpose assay 6.1 General <\/td>\n<\/tr>\n | ||||||
17<\/td>\n | 6.2 Assay selection 6.3 Kit or system selection <\/td>\n<\/tr>\n | ||||||
18<\/td>\n | 6.4 Considerations for various test types <\/td>\n<\/tr>\n | ||||||
19<\/td>\n | 6.5 User requirement specifications 6.5.1 General 6.5.2 Speed 6.5.3 Sample volume 6.5.4 In-process versus final release testing 6.5.5 Specificity <\/td>\n<\/tr>\n | ||||||
20<\/td>\n | 6.5.6 Sensitivity 7 Validation 7.1 General concepts <\/td>\n<\/tr>\n | ||||||
21<\/td>\n | 7.2 Selection of microorganisms for validation <\/td>\n<\/tr>\n | ||||||
22<\/td>\n | 7.3 Quality by design of method validation 7.4 Revalidation method <\/td>\n<\/tr>\n | ||||||
23<\/td>\n | 7.5 System validation 7.6 Use of reference material in validation 7.7 Acceptance criteria of targeted validation parameters <\/td>\n<\/tr>\n | ||||||
24<\/td>\n | 7.8 Precision 7.9 Detection limit 7.10 Accuracy <\/td>\n<\/tr>\n | ||||||
25<\/td>\n | 7.11 Robustness 7.12 Ruggedness 8 Points to take into account for the use and application of rapid microbial tests 8.1 Number and type of samples 8.2 Testing environment <\/td>\n<\/tr>\n | ||||||
26<\/td>\n | 8.3 Sensitivity 8.4 Specificity (organism detection) 8.5 Comparable test data <\/td>\n<\/tr>\n | ||||||
27<\/td>\n | 9 Investigation of positive sterility results 10 Training <\/td>\n<\/tr>\n | ||||||
28<\/td>\n | 11 Documentation 12 Reporting <\/td>\n<\/tr>\n | ||||||
29<\/td>\n | Annex\u20acA (informative) Exemplary Framework for identifying microbial contamination <\/td>\n<\/tr>\n | ||||||
30<\/td>\n | Annex\u20acB (informative) Risk analysis with Cellular Therapeutic Products related to input materials – Donor selection <\/td>\n<\/tr>\n | ||||||
31<\/td>\n | Annex\u20acC (informative) Risk analysis with Cellular Therapeutic Products related to input materials – Cell transformation and expansion <\/td>\n<\/tr>\n | ||||||
33<\/td>\n | Annex\u20acD (informative) Risk analysis with Cellular Therapeutic related to input materials – Packaging storage and administration <\/td>\n<\/tr>\n | ||||||
34<\/td>\n | Annex\u20acE (informative) Risk-based classification for monitoring practices for Cellular Therapeutic Product manufacturing <\/td>\n<\/tr>\n | ||||||
35<\/td>\n | Annex\u20acF (informative) Validation of rapid microbial test methods <\/td>\n<\/tr>\n | ||||||
37<\/td>\n | Annex\u20acG (informative) Microorganisms for validation of rapid microbial test methods <\/td>\n<\/tr>\n | ||||||
41<\/td>\n | Annex\u20acH (informative) Methods for rapid microbial testing <\/td>\n<\/tr>\n | ||||||
47<\/td>\n | Annex\u20acI (normative) Environmental control <\/td>\n<\/tr>\n | ||||||
48<\/td>\n | Bibliography <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":" BS ISO 24190. Biotechnology. Analytical Methods. Risk based approach for design and validation of methods for rapid microbial detection in bioprocesses<\/b><\/p>\n |