{"id":601861,"date":"2024-11-05T22:12:14","date_gmt":"2024-11-05T22:12:14","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/iso-19040-32018\/"},"modified":"2024-11-05T22:12:14","modified_gmt":"2024-11-05T22:12:14","slug":"iso-19040-32018","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/iso\/iso-19040-32018\/","title":{"rendered":"ISO 19040-3:2018"},"content":{"rendered":"
This document specifies a method for the determination of the estrogenic potential of water and waste water by means of a reporter gene assay utilizing stably transfected human cells. This reporter gene assay is based on the activation of the human estrogen receptor alpha.<\/p>\n
This method is applicable to:<\/p>\n
\u2014 fresh water;<\/p>\n
\u2014 waste water;<\/p>\n
\u2014 aqueous extracts and leachates;<\/p>\n
\u2014 eluates of sediments (fresh water);<\/p>\n
\u2014 pore water;<\/p>\n
\u2014 aqueous solutions of single substances or of chemical mixtures;<\/p>\n
\u2014 drinking water;<\/p>\n
\u2014 the limit of quantification (LOQ) of this method for the direct analysis of water samples is between 0,3 ng\/l and 1 ng\/l 17\u00df-estradiol equivalents (EEQ) based on the results of the international interlaboratory trial (see Annex F). The upper working range was evaluated [based on the results of the international interlaboratory trial (see Table F.3)] up to a level of 75 ng EEQ\/l. Samples showing estrogenic potencies above this threshold have to be diluted for a valid quantification. Extraction and pre concentration of water samples can prove necessary if their estrogenic potential is below the given LOQ.<\/p>\n","protected":false},"excerpt":{"rendered":"
Water quality \u2014 Determination of the estrogenic potential of water and waste water \u2014 Part 3: In vitro human cell-based reporter gene assay<\/b><\/p>\n\n\n
\n Published By<\/td>\n Publication Date<\/td>\n Number of Pages<\/td>\n<\/tr>\n \n ISO<\/b><\/a><\/td>\n 2018-08<\/td>\n 48<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":601875,"template":"","meta":{"rank_math_lock_modified_date":false,"ep_exclude_from_search":false},"product_cat":[218,2634],"product_tag":[],"class_list":{"0":"post-601861","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-13-060-70","7":"product_cat-iso","9":"first","10":"instock","11":"sold-individually","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product\/601861","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media\/601875"}],"wp:attachment":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media?parent=601861"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_cat?post=601861"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_tag?post=601861"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}