ASTM-F750 2012

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F750-87(2012) Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

Published By	Publication Date	Number of Pages
ASTM	2012	3

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Description

1.1 This practice covers a nonspecific, acute toxicity test used for detecting leachables from materials used in medical devices.

1.2 The liquids injected into the mouse are those obtained by Practice F619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 Two procedures are outlined: Method A for intravenous injection and Method B for intraperitoneal injection.

1.4 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.

1.5 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.

Additional information

Standard Title	F750-87(2012) Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse
Published Code	ASTM
Publication Date	2012
Pages Count	3

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ASTM-F750 2012

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